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Figure 5. a) Brain IL-17 and b) HMGB1 levels were significantly higher in the NSAID group compared to its vehicle (p = 0.016 and p = 0.016, respectively). c) Brain IL-6 levels were similar between the two groups (p = 0.67). d) Significantly greater serum <t>LBP</t> and <t>e)</t> <t>occludin</t> levels were found in the NSAID group compared to the vehicle (p = 0.006 and p = 0.016, respectively). *p < 0.05 vs. controls.
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Figure 5. a) Brain IL-17 and b) HMGB1 levels were significantly higher in the NSAID group compared to its vehicle (p = 0.016 and p = 0.016, respectively). c) Brain IL-6 levels were similar between the two groups (p = 0.67). d) Significantly greater serum <t>LBP</t> and <t>e)</t> <t>occludin</t> levels were found in the NSAID group compared to the vehicle (p = 0.006 and p = 0.016, respectively). *p < 0.05 vs. controls.
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Figure 5. a) Brain IL-17 and b) HMGB1 levels were significantly higher in the NSAID group compared to its vehicle (p = 0.016 and p = 0.016, respectively). c) Brain IL-6 levels were similar between the two groups (p = 0.67). d) Significantly greater serum LBP and e) occludin levels were found in the NSAID group compared to the vehicle (p = 0.006 and p = 0.016, respectively). *p < 0.05 vs. controls.

Journal: Turkish journal of medical sciences

Article Title: Leaky gut and inflammatory biomarkers in a medication overuse headache model in male rats.

doi: 10.55730/1300-0144.5763

Figure Lengend Snippet: Figure 5. a) Brain IL-17 and b) HMGB1 levels were significantly higher in the NSAID group compared to its vehicle (p = 0.016 and p = 0.016, respectively). c) Brain IL-6 levels were similar between the two groups (p = 0.67). d) Significantly greater serum LBP and e) occludin levels were found in the NSAID group compared to the vehicle (p = 0.006 and p = 0.016, respectively). *p < 0.05 vs. controls.

Article Snippet: Serum LBP (E-EL-R0589) and occludin levels (E-EL-R2503) and brain tissue HMGB1 (E-EL-R0505) were measured with sandwich-type rat ELISA kits from Elabscience Biotechnology Inc., Houston, TX, USA.

Techniques: